BY-Chanchal Ganesh Rathod, Pranjali Prakash Sadigale.-
Volume 1 Issue 1 (May-Aug) 2024, Article 9 (pp.78-88)
Key Points
Question: How does cognitive rehabilitation impact cognitive function and daily living activities in individuals with Alzheimer’s Disease compared to no intervention or standard care?
Findings: This systematic review of 20 studies, including randomized controlled trials and cohort studies, demonstrated that cognitive rehabilitation significantly improves cognitive function and daily living activities in individuals with Alzheimer’s Disease. Participants undergoing cognitive rehabilitation showed notable improvements in cognitive assessments and functional outcomes, with results being statistically significant.
Meaning: Cognitive rehabilitation offers substantial benefits over standard care for managing Alzheimer’s Disease, highlighting its potential as an effective intervention for enhancing cognitive and functional outcomes in affected individuals.
Abstract
Importance: Alzheimer’s Disease (AD) represents a critical challenge in public health due to its profound impact on cognitive function and daily living activities. As AD prevalence increases globally, identifying effective interventions is essential for improving patient outcomes and quality of life.
Objective: This systematic review aims to evaluate the efficacy of cognitive rehabilitation in enhancing cognitive function and daily living activities among individuals with Alzheimer’s Disease. The review focuses on treatment outcomes related to cognitive and functional improvements, comparing cognitive rehabilitation against no intervention or standard care.
Evidence Review: A comprehensive search was conducted in databases including PubMed, Cochrane Library, and PsycINFO, covering studies published from January 2000 to September 2023. Studies were selected based on criteria that included randomized controlled trials (RCTs) and cohort studies comparing cognitive rehabilitation with standard care or no intervention. Inclusion criteria were based on relevance to cognitive and functional outcomes in AD. Quality assessment of studies was performed using the Cochrane Risk of Bias Tool and the Newcastle-Ottawa Scale.
Findings: This review incorporated 18 studies, consisting of 12 RCTs and 6 cohort studies, involving a total of 1,500 participants. The analysis revealed that cognitive rehabilitation significantly improved cognitive function and daily living activities compared to standard care or no intervention. Statistically significant enhancements were observed in cognitive assessments and measures of daily functioning, with a notable positive impact on overall quality of life for AD patients.
Conclusions and Relevance: Cognitive rehabilitation is shown to be an effective intervention for improving cognitive function and daily living activities in individuals with Alzheimer’s Disease. The findings support the incorporation of cognitive rehabilitation into standard treatment protocols for AD, emphasizing its potential to enhance patient outcomes and inform future clinical practice and research strategies.
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